Pearly Caps Skin Whitening Formula which:

Pearly Caps

Skin Whitening Formula which:

– Evens out complexion
– Helps prevent darkening of the skin
– Supports enhancement of cutaneous brightness
– Helps fade hyperpigmentation dark spots

BENEFITS OF THE INGREDIENTS

Glutathione

– It belongs to the Thiol group for its reported significant associations with skin color

IT IS MADE UP OF 3 AMINO ACIDS:
-Glutamate
-Cysteine
-Glycine

Aside from its many biological functions, Glutathione has an evident hypopigmenting effect.

Mechanisms of Thiol Action

1) Direct Effects on the enzyme Tyrosinase
2) Indirect Effects on transition from its path
Eumelanogenesis in the path of Phaeomelanogenesis
Villarama, C.D., et al(2005)

When will the effect of Glutathione be seen?

The first results can be seen within a month

Significant results can take from 3 months to several years depending on how dark the skin color is:
Significant effect may need 1-3months, 3-6months, 6-12months, and 2 years (or more) in medium brown skin, dark brown skin, very dark skin, and black skin, respectively.

Sonthalia, S.,et al (2016)

Vitamin C

-Ascorbic Acid (vitamin C, AsA), is the most plentiful antioxidant in human skin

– The idea behind using antioxidants for skin-lightening activities lies in the hypothesis that the oxidative effect of UV-irradiation contributes to activation of melanogenesis

As it interferes with melanin synthesis
-reducing oxidized dopaquinone
-interrupting DHICA oxidation
-preventing action of tyrosinase

Int J Mol Sci. 2009 Sep; 10(9): 4066–4087

Alpha Lipoic Acid

It has been documented that the mechanism underlying skin protection by LA may be specific to its antioxidant potential to scavenge generated free radicals

– Contributes to the regeneration of Glutathione.

Milk Thistle

– Contains Silybinin (or Silybin) which is the active ingredient of Silymarin (a flavonolignan compound found in the extract of the milk thistle plant) and is a powerful antioxidant.

– It appears to have chemopreventive properties against cancer, thereby offering protection against chemical or radiation-induced skin injuries.

– Contributes to the protection of the skin from UV damage, preventing photoaging and hyperpigmentation especially in areas with a high risk of sun exposure

Clin Dermatol. 2009 Sep–Oct; 27(5): 479–484

No EOF Notification: 73573/29-7-2021 – The EOF notification number does not constitute a marketing authorization license from EOF.

Dietary supplements should not be considered a substitute for a rich and balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose.

Keep away from small children. The product must not be intended for the prevention, treatment or cure of human disease. Consult your doctor if you are under treatment or have health problems.

Characteristics of Human Skin Color

• The color of human skin is mainly determined by the two types of melanin, the black-brown Eumelanin and the yellow-red pheomelanin

Melanogenesis disorders

Disturbances of the melanin production pathway lead to the formation of dark or light-colored spots on the skin (pigmentation).

Dysregulation of the tyrosinase enzyme is the main cause of melanogenesis inhibition

Hyperpigmentation is the darkening or increase in the natural color of the skin usually due to an increased deposition of melanin (hypermelanosis)

Less frequently, it may be caused by the deposition in the dermis of endogenous or exogenous pigments, such as hemosiderin, iron, or heavy metals

The excess of melanin in the basal and suprabasal layers of the skin is due to either an abnormally high number of melanocytes or a normal melanocyte population. These abnormalities may be due to both acquired and genetic factor

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